Pentafluorophenylcorrole-D-galactose conjugates
Pentafluorophenylcorrole-D-galactose conjugates
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DOI：
10.1016/j.tetlet.2012.09.038
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发表时间：
2012-11-21
影响因子：
1.8
通讯作者：
Roeder, Beate
中科院分区：
文献类型：
--
作者：
Cardote, Teresa A. F.;Barata, Joana F. B.;Roeder, Beate
以5，10，15-三(五氟苯基)考罗与1，2:3，4-di-O-isopropylidene-alpha-D-galactopyranose.反应，合成了新的考罗-D-半乳糖结合物用核磁共振波谱和质谱仪对单取代异构体进行了充分的表征。后者的研究可用于区分这两个共轭异构体。对所分离的主偶联物的光物理性质和对Jurkat细胞的光动力学效应进行了评价。(C)2012爱思唯尔有限公司。保留所有权利。
New corrole-D-galactose conjugates were synthesized from the reaction of 5,10,15-tris(pentafluorophenyl)corrole and 1,2:3,4-di-O-isopropylidene-alpha-D-galactopyranose. The monosubstituted isomers were fully characterized by NMR spectroscopy and mass spectrometry. The latter studies can be used to differentiate the two conjugate isomers. The photophysical properties and the photodynamic effect on Jurkat cells were evaluated for the main conjugate isolated. (C) 2012 Elsevier Ltd. All rights reserved.