Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure
Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure
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DOI：
10.1097/01.ccm.0000090001.91640.45
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发表时间：
2003-11-01
影响因子：
8.8
通讯作者：
中科院分区：
文献类型：
--
作者：
目的呼气末正压(PEEP)和复张动作(RMS)可部分逆转肺不张，减轻呼吸机相关性肺损伤。这项研究的目的是评估a)接受低潮气量和高水平PEEP的急性肺损伤和急性呼吸窘迫综合征(ALI/ARDS)患者的RM对动脉氧合和氧合支持需求(FiO2/PEEP)的影响的大小和持续时间；以及b)可归因于RMS的不良呼吸和循环事件的频率。
ObjectivePositive end-expiratory pressure (PEEP) and recruitment maneuvers (RMs) may partially reverse atelectasis and reduce ventilation-associated lung injury. The purposes of this study were to assess a) magnitude and duration of RM effects on arterial oxygenation and on requirements for oxygenation support (Fio 2/PEEP) in patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) receiving ventilation with low tidal volumes and high levels of PEEP; and b) frequency of adverse respiratory and circulatory events attributable to RMs.Design