The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering.
The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering.
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DOI：
10.3390/biomedicines5010004
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发表时间：
2017-01-06
期刊：
影响因子：
4.7
通讯作者：
Osborn SL
中科院分区：
文献类型：
--
作者：
Chan YY;Sandlin SK;Kurzrock EA;Osborn SL
许多病理过程，包括神经原性膀胱和恶性肿瘤，需要膀胱重建，这是目前使用肠组织进行。然而，使用肠组织会使患者出现代谢异常、膀胱结石和其他长期后遗症，因此需要安全可靠的膀胱组织来源。干细胞生物学的进步已经将干细胞弹射到许多当前组织再生和生物工程策略的中心。本文就干细胞在膀胱组织工程中的应用作一综述。
Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder stones, and other long-term sequelae, raising the need for a source of safe and reliable bladder tissue. Advancements in stem cell biology have catapulted stem cells to the center of many current tissue regeneration and bioengineering strategies. This review presents the recent advancements in the use of stem cells in bladder tissue bioengineering.