Sensory memory for odors is encoded in spontaneous correlated activity between olfactory glomeruli
Sensory memory for odors is encoded in spontaneous correlated activity between olfactory glomeruli
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DOI：
10.1162/089976606774841558
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发表时间：
2006-01-01
影响因子：
2.9
通讯作者：
Galizia, CG
中科院分区：
文献类型：
--
作者：
Galán, RF;Weidert, M;Galizia, CG
感觉记忆是感觉刺激在神经系统中的短暂持续，例如视觉系统中的图像记忆。然而，对嗅觉记忆的机制知之甚少。因此，我们分析了气味刺激对蜜蜂大脑中第一个气味处理网络的影响，触角叶，它对应于脊椎动物的嗅球。我们用钙敏感染料对输出神经元进行染色，并测量刺激前后肾小球自发活动的模式。根据赫布的学习理论，这种单一气味的呈现改变了肾小球自发活动的相对时间。此外，在气味呈现后的最初几分钟内，自发活动波动之间的相关性足以重建刺激。由于自发活动在大脑中无处不在，可修改的波动可以为赫布混响提供理想的基底。其他神经系统的感觉记忆
Sensory memory is a short-lived persistence of a sensory stimulus in the nervous system, such as iconic memory in the visual system. However, little is known about the mechanisms underlying olfactory sensory memory. We have therefore analyzed the effect of odor stimuli on the first odor-processing network in the honeybee brain, the antennal lobe, which corresponds to the vertebrate olfactory bulb. We stained output neurons with a calcium-sensitive dye and measured across-glomerular patterns of spontaneous activity before and after a stimulus. Such a single-odor presentation changed the relative timing of spontaneous activity across glomeruli in accordance with Hebb's theory of learning. Moreover, during the first few minutes after odor presentation, correlations between the spontaneous activity fluctuations suffice to reconstruct the stimulus. As spontaneous activity is ubiquitous in the brain, modifiable fluctuations could provide an ideal substrate for Hebbian reverberations and. sensory memory in other neural systems.