Approaches to the high-throughput synthesis of analogues of dihydroaeruginoic acid

Approaches to the high-throughput synthesis of analogues of dihydroaeruginoic acid
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DOI:
10.1071/ch99162
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发表时间:
2000-01-01
影响因子:
1.1
通讯作者:
Marshall, RL
Marshall, RL
中科院分区:
化学4区
文献类型:
--
作者:
Loughlin, WA;Knevitt, SA;Marshall, RL

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确定了一种二氢铜绿酸(1)的液相合成方法,用于高通量合成二氢铜绿酸类似物(1)。研究了固相合成二氢铜绿酸(1)的研究进展。用液相高通量合成法合成了二氢铜绿酸(1)的简单类似物(11a-f)。
A solution-phase synthesis of dihydroaeruginoic acid (1) was identified for its application towards the high-throughput synthesis of analogues of dihydroaeruginoic acid (1). Development of a solid-phase synthesis of dihydroaeruginoic acid (1) was examined. Simple analogues (11a-f) of dihydroaeruginoic acid (1) were obtained by using solution-phase high-throughput synthesis.