A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay
A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay
复制标题
DOI：
10.1080/00949650902737465
复制
发表时间：
2010-01-01
影响因子：
1.2
通讯作者：
Scheder, Regine
中科院分区：
文献类型：
--
作者：
Dette, Holger;Scheder, Regine
为了估计常见二元响应模型中的有效剂量水平艾德（α），文献中提出了几种参数和非参数估计量。在本文中，我们专注于非参数方法，并提出了一个详细的数值比较四种不同的方法来估计EDa非参数。的方法进行了简要的回顾，并通过详细的模拟研究其有限样本的性质进行了研究。此外，一个数据的例子来说明不同的概念。
To estimate the effective dose level ED(alpha) in the common binary response model, several parametric and nonparametric estimators have been proposed in the literature. In the present article, we focus on nonparametric methods and present a detailed numerical comparison of four different approaches to estimate the EDa nonparametrically. The methods are briefly reviewed and their finite sample properties are studied by means of a detailed simulation study. Moreover, a data example is presented to illustrate the different concepts.