Ultrasound Evidence of Early Fetal Growth Restriction after Maternal Malaria Infection
Ultrasound Evidence of Early Fetal Growth Restriction after Maternal Malaria Infection
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DOI：
10.1371/journal.pone.0031411
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发表时间：
2012-02-09
期刊：
影响因子：
3.7
通讯作者：
McGready, Rose
中科院分区：
文献类型：
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作者：
Rijken, Marcus J.;Papageorghiou, Aris T.;McGready, Rose
背景：间歇性预防治疗（IPT）是预防疟疾、减少贫血和低出生体重的主要策略，重点关注妊娠后半期。然而，宫内生长受限可能发生在怀孕早期。本研究的目的是通过比较受感染和未受感染妇女的胎儿双顶径 (BPD) 来衡量疟疾对怀孕前半段的影响，这些妇女的怀孕时间已在妊娠 14 周前通过冠臀长 (CRL) 准确确定。方法/主要发现：在 3,779 名居住在泰缅边境的妇女中，她们在 14 周之前生下了一名正常的单胎活产婴儿。 2001-10 以及通过 CRL 测量估算孕龄的人
Background: Intermittent preventive treatment (IPT), the main strategy to prevent malaria and reduce anaemia and low birthweight, focuses on the second half of pregnancy. However, intrauterine growth restriction may occur earlier in pregnancy. The aim of this study was to measure the effects of malaria in the first half of pregnancy by comparing the fetal biparietal diameter (BPD) of infected and uninfected women whose pregnancies had been accurately dated by crown rump length (CRL) before 14 weeks of gestation.Methodology/Principal Findings: In 3,779 women living on the Thai-Myanmar border who delivered a normal singleton live born baby between 2001-10 and who had gestational age estimated by CRL measurement