Anxiety Disorder Associated with the COVID-19 Pandemic Causes Deterioration of Blood Pressure Control in Primary Hypertensive Patients.
Anxiety Disorder Associated with the COVID-19 Pandemic Causes Deterioration of Blood Pressure Control in Primary Hypertensive Patients.
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DOI：
10.5222/mmj.2021.08364
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发表时间：
2021
影响因子：
--
通讯作者：
Caliskan M
中科院分区：
文献类型：
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作者：
Celik M;Yilmaz Y;Karagoz A;Kahyaoglu M;Cakmak EO;Kup A;Celik FB;Karaduman A;Kulahcioglu S;Izci S;Gecmen C;Caliskan M
新型冠状病毒病（COVID-19）在全球迅速蔓延，并引发焦虑症。最近的研究也表明，在COVID-19爆发期间，抑郁和焦虑的患病率有所增加。我们的目的是评估在大流行期间的焦虑和抑郁水平，并确定流行相关的压力对原发性高血压患者血压控制的影响。共有142名在大流行之前和期间继续使用相同降压药物的原发性高血压（HT）患者被纳入研究。对患者进行24小时动态血压监测（ABPM）和医院焦虑抑郁量表（HADS）问卷调查。我们回顾性分析了同一患者在大流行前一年的24小时ABPM记录。与大流行前相比，COVID-19爆发期间白天、夜间和24小时收缩压（SBP）水平以及白天、夜间和24小时舒张压（DBP）水平显著升高（p<0.001）。与HADS-A评分较低的患者相比，HADS-A评分较高（HADS-A ≥7）的患者血压升高幅度更大。2019冠状病毒病爆发造成的心理压力导致降压治疗未改变的控制性高血压患者的血压调节恶化。
The new coronavirus disease (COVID-19) has spread rapidly all over the world and caused anxiety disorders. Recent studies have also shown that the prevalence of depression and anxiety increased during the COVID-19 outbreak. We aimed to evaluate the anxiety and depression levels during the pandemic and identify the effect of pandemic-related stress on blood pressure (BP) control in primary hypertensive patients. A total of 142 patients with primary hypertension (HT) who continued to use the same antihypertensive drugs before and during the pandemic were included in the study. Twenty-four -hour Ambulatory Blood Pressure Monitoring (ABPM) and the Hospital Anxiety and Depression Scale (HADS) questionnaire were applied to patients. We retrospectively reviewed 24-h ABPM records of the same patients for the year before the pandemic. Daytime, nighttime and 24 -hour-systolic blood pressure (SBP) levels as well as daytime, nighttime, and 24- hour-diastolic blood pressure (DBP) levels , were significantly elevated during the COVID-19 outbreak compared to the pre-pandemic period (p<0.001). Higher HADS-A scores (HADS-A ≥7) were significantly associated with much greater increase in BP compared to the patients with lower HADS-A scores. Psychological stress due to the COVID-19 outbreak led to worsening of the regulation of BP in controlled hypertensive patients whose antihypertensive treatments did not change.