Gold nanoparticles-peptide based gas sensor arrays for the detection of food aromas
Gold nanoparticles-peptide based gas sensor arrays for the detection of food aromas
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DOI：
10.1016/j.bios.2012.10.096
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发表时间：
2013-04-15
影响因子：
12.6
通讯作者：
Di Natale, C.
中科院分区：
文献类型：
--
作者：
Compagnone, D.;Fusella, G. C.;Di Natale, C.
基于肽修饰的金纳米颗粒沉积在20 MHz石英晶体微天平上的气体传感器阵列已经实现。谷氨酸及其组成氨基酸和二肽已被用作配体。与单层修饰的QCM相比，使用金纳米颗粒实现了灵敏度的大幅增加（2个数量级）。对传感器的正己烷、水、三甲胺和乙醇的灵敏度进行了表征。对水的敏感性最高。利用由谷胱甘肽肽、巯基乙酸和七肽修饰的纳米金颗粒组成的气敏传感器阵列，研究了其对顺式-3-己烯醇、乙酸异戊酯、乙酸乙酯和松油烯-4-醇等典型食品香气在不同溶剂中的分辨能力。发现该阵列能够区分食物香味，响应取决于所用溶剂的极性。对真实的橄榄油样品的测试给出了具有缺陷的样品与非缺陷样品之间的令人满意的分离，证明了这种方法对于开发用于真实的样品的气体传感器阵列具有很高的潜力。(C)2012爱思唯尔有限公司版权所有。
A gas sensor array based on peptide modified gold nanoparticles deposited onto 20 MHz quartz crystal microbalances has been realized. Glutathione and its constituting aminoacids and dipeptides have been used as ligands. A great increase in sensitivity (2 orders of magnitude) was achieved using gold nanoparticles versus monolayer modified QCMs. The sensors have been charachterised in terms of sensitivity for hexane, water, trimethylammine and ethanol. Highest sensitivity was found for water. The ability to discriminate typical food aromas as cis-3-hexenol, isopentylacetate, ethylacetate, and terpinen-4-ol dissolved in different solvents was studied using a gas sensor array constituted by gold nanoparticles modified with the glutathione peptides, thioglycolic acid and an heptapeptide. The array was found able to discriminate the food aromas, the response being dependent on the polarity of the solvent used. Tests on real olive oil samples gave a satisfactory separation among samples having defects versus non defected samples demonstrating that this approach has high potential for the development of gas sensor arrays to be used in real samples. (C) 2012 Elsevier B.V. All rights reserved.