DEVELOPMENTAL DIFFERENCES IN TRACHEAL CARTILAGE MECHANICS

DEVELOPMENTAL DIFFERENCES IN TRACHEAL CARTILAGE MECHANICS
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DOI:
10.1203/00006450-198911000-00013
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发表时间:
1989-11-01
期刊:
影响因子:
3.6
通讯作者:
SHAFFER, TH
SHAFFER, TH
中科院分区:
医学3区
文献类型:
--
作者:
PENN, RB;WOLFSON, MR;SHAFFER, TH

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长度-张力特性进行了检查,从早产羔羊(n = 8)和成年绵羊(n = 7)切除气管环,以确定气管软骨的机械性能的发育差异。随着环被延长以增加插入点之间的距离,在复合体(包括膜部及其软骨插入部)和软骨沿着(通过切断膜部)中测量张力。回归线分析显示,与早产儿组相比,成人组的复合体和软骨的斜率显著更大。这些数据表明,与年龄相关的气管软骨力学差异是平行的,并可能导致先前确定的与年龄相关的气管顺应性差异。
Length-tension characteristics were examined in tracheal rings excised from preterm lambs (n = 8) and adult sheep (n = 7) to determine developmental differences in the mechanical properties of tracheal cartilage. Tension was measured in both the complex (comprised of the pars membranacea and its cartilagenous insertion) and the cartilage along (by severing the pars membranacea) as the ring was lengthened so as to increase the distance between the points of insertion. Analysis of regression lines show significantly greater slopes for both the complex and the cartilage in the adult group compared to the preterm group. These data revel that age-related differences in tracheal cartilage mechanics parallel and may contribute to age-related differences previously determined in tracheal compliance.