Major dietary patterns and cardiovascular risk factors from childhood to adulthood.: The Cardiovascular Risk in Young Finns Study
Major dietary patterns and cardiovascular risk factors from childhood to adulthood.: The Cardiovascular Risk in Young Finns Study
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DOI：
10.1017/s0007114507691831
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发表时间：
2007-07-01
影响因子：
3.6
通讯作者：
Viikari, Jorma
中科院分区：
文献类型：
--
作者：
Mikkilae, Vera;Rasnan, Leena;Viikari, Jorma
关于单一营养素对心血管疾病风险的影响的研究往往给出不确定的结果。最近关于饮食模式的研究为饮食对心血管疾病风险的整体影响提供了有希望的信息。青年芬兰人的心血管风险研究是一项正在进行的前瞻性队列研究，至今已进行了21年的跟踪调查。研究对象为基线时的儿童和青少年(3-18岁，1768人)和最近一次随访研究中的成年人(24-39岁，1037人)。我们调查了两种主要饮食模式和几种心血管疾病危险因素之间的关系。在重复测量的纵向分析中，使用多元混合线性回归模型，传统的饮食模式(以大量食用黑麦、土豆、黄油、香肠、牛奶和咖啡为特征)与男女的总胆固醇和低密度脂蛋白浓度、载脂蛋白B和C反应蛋白浓度独立相关，也与女性的收缩压和胰岛素水平以及男性的同型半胱氨酸浓度独立相关(P
Studies on the impact of single nutrients on the risk of CVD have often given inconclusive results. Recent research on dietary patterns has offered promising information on the effects of diet as a whole on the risk of CVD. The Cardiovascular Risk in Young Finns Study is an ongoing, prospective cohort study with a 21-year follow-up to date. The subjects were children and adolescents at baseline (3-18 years, n 1768) and adults at the latest follow-up study (24-39 years, n 1037). We investigated the associations between two major dietary patterns and several risk factors for CVD. In longitudinal analyses with repeated measurements, using multivariate mixed linear regression models, the traditional dietary pattern (characterised by high consumption of rye, potatoes, butter, sausages, milk and coffee) was independently associated with total and LDL cholesterol concentrations, apolipoprotein B and C-reactive protein concentrations among both genders, and also with systolic blood pressure and insulin levels among women and concentrations of homocysteine among men (P