Use of free vascularized bone grafts in the treatment of bone tumors.
Use of free vascularized bone grafts in the treatment of bone tumors.
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DOI：
10.1097/00003086-198305000-00006
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发表时间：
1983-05
影响因子：
4.2
通讯作者：
J. Moore;Andrew J. Weiland;R. K. Daniel
中科院分区：
文献类型：
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作者：
J. Moore;Andrew J. Weiland;R. K. Daniel
五年来对十例侵袭性骨病变进行一期切除并通过自体腓骨立即重建进行治疗的经验表明，与游离骨移植相比，血管化移植具有优势。该手术针对 7 例局部侵袭性骨肿瘤和 3 例 III 型先天性胫骨假关节进行。在大型嵌入骨移植中，血管化腓骨积极参与愈合过程，而不是像传统骨移植那样仅仅充当诱导蠕变替代的框架。除1例外，移植物均愈合并逐渐肥大，未出现肿瘤复发。对于直径小于 6 厘米的缺损，传统骨移植通常是成功的。然而，对于大于6厘米的缺损或血管化不良的床，血管化腓骨移植物可以预防无血管化皮质骨和松质骨移植物常见的疲劳骨折、合并失败和骨不连等并发症。
A five-year experience with ten cases of primary resection of aggressive bone lesions treated by immediate reconstruction with autologous fibula demonstrates the advantages of vascularized, compared with free bone, graft. The procedure was performed for locally aggressive bone tumors in seven cases, and for Type III congenital pseudarthroses of the tibia in three cases. In large intercalary bone grafts, the vascularized fibula actively participates in the healing process, rather than serving merely as a framework for inductive creeping substitution, as is the case in conventional bone grafts. With the exception of one case, the grafts united and progressively hypertrophied, and there was no tumor recurrence. For defects less than 6 cm in diameter, conventional bone grafts usually prove successful. However, for defects greater than 6 cm or in a poorly vascularized bed, the vascularized fibular graft can prevent such complications as fatigue fracture, failure of incorporation, and nonunion that are frequently seen with nonvascularized cortical and cancellous bone grafts.