Microwave-Induced Thermal Acoustic Tomography for Breast Tumor Based on Compressive Sensing

Microwave-Induced Thermal Acoustic Tomography for Breast Tumor Based on Compressive Sensing
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DOI:
10.1109/tbme.2012.2233737
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发表时间:
2013-05
影响因子:
4.6
通讯作者:
Xiaozhang Zhu;Zhiqin Zhao;Jinguo Wang;J. Song;Q. Liu
Xiaozhang Zhu;Zhiqin Zhao;Jinguo Wang;J. Song;Q. Liu
中科院分区:
工程技术2区
文献类型:
--
作者:
Xiaozhang Zhu;Zhiqin Zhao;Jinguo Wang;J. Song;Q. Liu

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微波诱导热声层析成像(MITAT)是一种基于生物组织电学特性的生物医学组织成像技术。它具有高对比度和高空间分辨率的优点。图像重建方法一直是MITAT中的关键问题。本文提出了一种压缩感知(CS:compressive sensing)成像方法。压缩感知(CS)是最近开发的稀疏信号表示和分析框架,其使用低采样率或提高成像质量来处理医学成像测量。CS-MITAT成像方法将CS理论应用于用于乳腺肿瘤成像的MITAT。在该方法中,建立一个过完备字典,在空间域进行稀疏测量。这种处理大大节省了测量时间。通过对真实的乳腺肿瘤组织的仿真和实验,验证了该方法的可行性和有效性。与MITAT研究中使用的常规时间反转镜方法相比,CS-MITAT通过使用显著更少的声学传感器位置或扫描时间提供相同的峰值信噪比成像质量。
Microwave-induced thermal acoustic tomography (MITAT) is an innovative technique to image biomedical tissues based on their electric properties. It has the advantages of both high contrast and high spatial resolution. Image reconstruction method in MITAT is always a critical issue. In this paper, a CS-MITAT (CS: compressive sensing) imaging method is proposed. Compressive sensing (CS) is a recently developed sparse signal representation and analysis framework which handles medical imaging measurements using low sampling rate or increasing imaging quality. The CS-MITAT imaging method applies CS theory to the MITAT for breast tumor imaging. In this method, an over-complete dictionary is established to make sparse measurements in the spatial domain. This treatment greatly saves measurement time. Simulations and experiments with real breast tumor tissues demonstrate the feasibility and effectiveness of the method. Compared with conventional time reversal mirror method which has been used in MITAT research, CS-MITAT provides the same peak signal-to-noise ratio imaging quality by using significantly fewer acoustic sensor positions or scanning times.