Drinking water constituents and disease
Drinking water constituents and disease
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DOI：
10.1093/jn/138.2.423s
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发表时间：
2008-02-01
影响因子：
4.2
通讯作者：
Rylander, Ragnar
中科院分区：
文献类型：
--
作者：
Rylander, Ragnar
过去 50 年来的多项流行病学调查表明，心血管疾病的风险与饮用水硬度或其镁和钙含量之间存在关联。 50 年前日本的一项研究首次提出的另一个参数是水的酸度。已知酸负荷影响肾小管中钙和镁的重吸收。干预研究表明，酸碱条件影响矿物质的稳态。回顾了使用镁、钙和碳酸氢盐进行干预研究的数据。一些研究发现，与饮用水相关的健康影响可能是由于体内酸性条件导致尿液中矿物质排泄增加造成的，饮用水中应含有足够量的碳酸氢盐以防止这种影响。
Several epidemiological investigations over the last 50 y have demonstrated a relation between risk for cardiovascular disease and drinking water hardness or its content of magnesium and calcium. An additional parameter, first suggested in a study from Japan 50 y ago, is the acidity of the water. It is known that acid load influences the reabsorption of calcium and magnesium in the renal tubuli. Intervention studies have shown that acid-base conditions influence the homeostasis of minerals. Data from intervention studies using magnesium, calcium, and hydrogen carbonate are reviewed. It is suggested that the health effects related to drinking water found in some studies may be caused by an increased urinary excretion of minerals induced by acid conditions in the body and that drinking water should contain sufficient amounts of hydrogen carbonate to prevent this effect.