Combined Epithelial-Myoepithelial Lesions of the Breast.

Combined Epithelial-Myoepithelial Lesions of the Breast.
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DOI:
10.1016/j.path.2012.06.003
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发表时间:
2012-09-01
影响因子:
--
通讯作者:
Hayes, Malcolm M
Hayes, Malcolm M
中科院分区:
其他
文献类型:
--
作者:
Ali, Rola H;Hayes, Malcolm M

文献摘要

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乳腺上皮-肌上皮增殖是一组形态不清的异质性病变,其特征是双重分化为导管(腔)和肌上皮细胞。它们包括肿瘤和非肿瘤实体,它们具有重叠的形态特征,可能导致诊断困难。其中许多实体是低级别或不确定的恶性潜能,但其中一些罕见病变的生物学仍有待阐明。本文讨论了乳腺上皮-肌上皮病变的鉴别诊断,并强调了其中一些实体的形态特征。
Epithelial-myoepithelial proliferations of the breast are a heterogeneous poorly defined group of lesions characterized morphologically by dual differentiation into ductal (luminal) and myoepithelial cells. They include neoplastic and non-neoplastic entities that have overlapping morphologic features that may give rise to diagnostic difficulty. Many of these entities are low grade or of uncertain malignant potential but the biology of some of these rare lesions remains to be elucidated. This article discusses the differential diagnosis of epithelial-myoepithelial lesions of the breast and highlights the morphologic features of some of these entities.