New secosteroids from a gorgonian of the genus Muricella

New secosteroids from a gorgonian of the genus Muricella
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DOI:
10.1021/np980220e
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发表时间:
1998-11-01
影响因子:
5.1
通讯作者:
Shin, J
Shin, J
中科院分区:
生物学2区
文献类型:
--
作者:
Seo, Y;Cho, KW;Shin, J

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从采自韩国济州岛的柳珊瑚属柳珊瑚中分离得到4个新的9,10-开环甾体--Calicoferols F-I(2-5)。这些化合物的结构已通过组合光谱法确定。Calicoferols对PLA具有明显的细胞毒性和抑制活性(2)。
Calicoferols F-I (2-5), four new 9,10-secosteroids, have been isolated from a gorgonian of the genus Muricella collected from Jaeju Island, Korea. The structures of these compounds have been determined by combined spectroscopic methods. Calicoferols exhibited significant cytotoxicity and inhibitory activity against PLA(2).