VARIABILITY OF THE CONFIGURATION OF MAXIMUM EXPIRATORY FLOW-VOLUME CURVES
VARIABILITY OF THE CONFIGURATION OF MAXIMUM EXPIRATORY FLOW-VOLUME CURVES
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DOI：
10.1152/jappl.1979.46.3.565
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发表时间：
1979-01-01
影响因子：
3.3
通讯作者：
MEAD, J
中科院分区：
文献类型：
--
作者：
TIEN, YK;ELLIOTT, EA;MEAD, J
用计算机技术研究最大呼气流量-容积（MEFV）曲线的构型的可变性，其依据是斜率比SR（SR = d·ovrhdot·V/dV·div. V/V，其中V是瞬时流量，V是剩余体积以上的体积增量。对20名正常受试者（年龄23-55岁）的每名受试者，在一个单一的场合，并在至少1周后再次推导出大约4条SR-V曲线，每条曲线基于3-5条平滑和平均的MEFV曲线。个体曲线在很大程度上是可重现的，在大多数体积下SR的最大差异为0.3-1 U[单位]，但经常显示随体积的显著但可重现的波动。这些对应于迄今未被认识到的最大呼气流量的不规则性，可能反映了流量限制位置的突然变化。
With a computer technique variability of the configuration of maximum expiratory flow-volume (MEFV) curves was studied in terms of slope ratio, SR. (SR = d.ovrhdot.V/dV .div. .ovrhdot.V/V, where .ovrhdot.V is the instantaneous flow and V is the volume increment above residual volume.) Approximately 4 SR-V curves, each based on 3-5 smoothed and averaged MEFV curves, were derived for each of 20 normal subjects (aged 23-55 yr) on a single occasion, and again at least 1 wk later. Individual curves were largely reproducible, the maximum difference in SR at most volumes being 0.3-1 U[units], but frequently showed substantial yet reproducible fluctuations with volume. These corresponded to hitherto unrecognized irregularities of maximum expiratory flow that may reflect sudden changes in the location of flow limitation.