Excimer laser ablation in a human eye. Case report.
Excimer laser ablation in a human eye. Case report.
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人眼中的准分子激光烧蚀。
DOI：
10.1001/archopht.1989.01070010659013
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发表时间：
1989
影响因子：
--
通讯作者：
S. Klyce
中科院分区：
文献类型：
--
作者：
M. McDonald;H. Kaufman;J. Frantz;S. Shofner;B. Salmeron;S. Klyce
致编辑。 —使用准分子激光烧蚀角膜组织来矫正光学误差，例如近视、远视和散光，最初是由纽约州哥伦比亚大学爱德华·S·哈克尼斯眼科研究所的 Stephen Trokel 医学博士提出的。我们报告了一名接受准分子激光消融术的患者的病例，该术式旨在使假定失明的眼睛变平角膜。这是在美国食品和药物管理局授予 Trokel 博士的研究设备豁免支持下进行的早期人类安全性和有效性“盲眼”试验的一部分。激光消融后 7 周内，患者的视力明显为功能性失明而非生理性失明，视力为 20/25，未经矫正则为 20/20。随访6个月后，角膜保持清晰，视力稳定。这是，
To the Editor. —The use of the excimer laser to ablate corneal tissue for the correction of optical errors, such as myopia, hyperopia, and astigmatism, was first suggested by Stephen Trokel, MD, of the Edward S. Harkness Eye Institute, Columbia University, New York, NY. We report a case of a patient who received excimer laser ablation that was designed to flatten the cornea in a putatively blind eye. This was performed as part of the early human safety and efficacy "blind eye" trials under the aegis of the Investigational Device Exemption granted by the Food and Drug Administration to Dr Trokel. Within 7 weeks of laser ablation, the patient, who had apparently been suffering from functional rather than physiologic blindness, had a visual acuity of 20/25 and then 20/20 without correction. After 6 months of follow-up, the cornea remained clear and the visual acuity appeared to be stable. This is,