Effect of Polygonum tinctoriumextract against gingival inflammation

Effect of Polygonum tinctoriumextract against gingival inflammation
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何首乌提取物抗牙龈炎症的作用

DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
S. Takashiba
S. Takashiba
中科院分区：
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文献类型：
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作者：
K. Hatanaka;Kyoko Fuke;K. Seno;T. Tomiyama;K. Iwaki;T. Kunikata;N. Masaki;S. Fukuda;H. Maeda;H. Arai;S. Takashiba

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An indigo dye plant, Polygonum tinctorium has been shown to have anti-inflammatory and antibacterial effects against pathogens causing periodontitis. In this study, the effect of Polygonum tinctorium extract on gingival inflammation was investigated in a double-blind fashion. Thirty patients with chronic periodontitis who had received supportive periodontal therapy (SPT) were enrolled. All subjects rubbed one gram of jell including Polygonum tinctorium extract on the gingiva three times per day after each meal and oral care for ten weeks. The clinical examinations of plaque index (PlI), probing pocket depth (PPD) and bleeding score (BOP) on four subjective teeth were performed before test and after five and ten weeks. We also measured the weight of gingival crevicular fluid (GCF) and TNF-αlevels in the GCF at same periods. 連絡先:畑中加珠 〒 700-8525 岡山県岡山市鹿田町 2-5-1 岡山大学大学院医歯薬学総合研究科歯周病態学分野 Kazu Hatanaka Department of Pathophysiology-Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences 2-5-1 Shikata-cho, Okayama 700-8525, Japan E-mail : kazu_t@md.okayama-u.ac.jp 167