Confocal laser endomicroscopy in the "in vivo" histological diagnosis of the gastrointestinal tract
Confocal laser endomicroscopy in the "in vivo" histological diagnosis of the gastrointestinal tract
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DOI：
10.3748/wjg.15.5770
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发表时间：
2009-12-14
影响因子：
4.3
通讯作者：
De Palma, Giovanni D.
中科院分区：
文献类型：
--
作者：
De Palma, Giovanni D.
小型化方面的最新技术进步使得共焦扫描显微镜可以集成到传统的柔性内窥镜或经内窥镜探头中，这种技术现在称为共焦内窥镜或共焦激光内窥镜。这项新开发的技术使内窥镜医师能够在内窥镜检查过程中收集胃肠粘膜的实时体内组织学图像或“虚拟活检”，并激发了人们对该技术在临床胃肠病学中应用的浓厚兴趣。本综述旨在评估技术方面的当前数据以及这项新技术在临床胃肠病学中的效用及其未来的潜在影响，特别是在胃肠道肿瘤的筛查或监测方面。 (C) 2009 WJG 出版社和百事登。版权所有
Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope, or into trans-endoscopic probes, a technique now known as confocal endomicroscopy or confocal laser endomicroscopy. This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or "virtual biopsies" of the gastrointestinal mucosa during endoscopy, and has stimulated significant interest in the application of this technique in clinical gastroenterology. This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future, particularly in the screening or surveillance of gastrointestinal neoplasia. (C) 2009 The WJG Press and Baishideng. All rights reserved