Auditory temporal processing deficits in patients with insular stroke
Auditory temporal processing deficits in patients with insular stroke
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DOI：
10.1212/01.wnl.0000230197.40410.db
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发表时间：
2006-08-22
期刊：
影响因子：
9.9
通讯作者：
Luxon, L. M.
中科院分区：
文献类型：
--
作者：
Bamiou, D. -E.;Musiek, F. E.;Luxon, L. M.
目的：探讨脑岛及邻近区脑卒中患者的中枢听觉功能。方法：作者招募了8例影响脑岛及其邻近区域的脑卒中患者和8例神经正常对照（与患者年龄、性别、惯用手和听力阈值相匹配）。3例患者的病变不包括邻近的听觉区，5例包括其他听觉结构。作者进行了纯音听力测量和鼓室测量，以及一组中央听觉测试，其中包括二分数字，以及三个时间测试，持续时间模式，频率模式和噪声测试中的间隙。他们从医院记录中收集了症状和急性期神经心理学评估数据。结果：所有对照组中央听觉测试结果正常。颞叶测试在其他听觉区域未受影响的所有三种情况下都给出了异常结果，在其他五种情况下也是如此。噪声测试结果3例对侧异常，5例双侧异常。在急性期，中枢性听觉缺陷不与认知障碍共存。结论：与神经影像学研究一致，岛叶病变可能影响中枢听觉功能，特别是时间分辨率和序列。
Objective: To assess central auditory function in a series of patients with stroke of the insula and adjacent areas. Methods: The authors recruited eight patients with stroke affecting the insula and adjacent areas and eight neurologically normal controls (matched to the patients for age, sex, handedness, and hearing thresholds). The lesion spared the adjacent auditory areas in three patients and included other auditory structures in five cases. The authors conducted pure-tone audiometry and tympanometry and a central auditory test battery, which included the dichotic digits, and three temporal tests, the duration pattern, frequency pattern, and gaps in noise tests. They collected information from the hospital notes on symptoms at presentation and neuropsychological assessment data during the acute phase. Results: The central auditory tests gave normal results in all controls. The temporal tests gave abnormal results in all three cases in which other auditory areas were spared, as well as in the other five cases. Results of the gaps in noise test were abnormal contralaterally to the lesion in three and bilaterally in five cases. The central auditory deficits did not cosegregate with the presence of cognitive impairment during the acute stage. Conclusion: Insular lesions may affect central auditory function and, in particular, temporal resolution and sequencing, consistent with neuroimaging studies.