Comparison of image quality and lesion diagnosis in abdominopelvic unenhanced CT between reduced-dose CT using deep learning post-processing and standard-dose CT using iterative reconstruction: A prospective study
Comparison of image quality and lesion diagnosis in abdominopelvic unenhanced CT between reduced-dose CT using deep learning post-processing and standard-dose CT using iterative reconstruction: A prospective study
复制标题
使用深度学习后处理的减量CT与使用迭代重建的标准剂量CT在腹部盆腔平扫CT中的图像质量和病变诊断的比较：一项前瞻性研究
DOI：
10.1016/j.ejrad.2021.109735
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发表时间：
2021-04-28
影响因子：
3.3
通讯作者：
Jin, Zhengyu
中科院分区：
文献类型：
--
作者：
Wang, Xiao;Zheng, Fuling;Jin, Zhengyu
目的：比较使用深度学习（DL）后处理的减少剂量腹盆非增强CT（CT）与使用迭代重建（IR）的标准剂量CT的图像质量和病变诊断。方法：251例患者分别接受了两次相同范围的连续腹盆非增强CT扫描，包括标准和减少剂量。在A组中，通过（混合30%）IR重建标准剂量数据。在B组中，通过滤波反投影重建来重建减少剂量数据以获得B1组图像，并使用DL算法（NeuAI去噪，东软医疗，沈阳，中国）以50%和100%权重分别进行后处理以获得B2和B3组图像。测量肝脏、第二腰椎椎体、竖脊肌和腹部皮下脂肪的CT值。比较CT值、噪声水平、信噪比（SNR）、对比噪声比（CNRs）、辐射剂量和图像质量主观评分。结果：B3组和B1组的噪声水平分别最低和最高（P <0.001），B3组和B1组的噪声水平分别最低和最高（P < 0.001）。B3组的SNR和CNR最高（P < 0.001）。与A组相比，B组的辐射剂量平均减少71.5%。A、B2组主观评分最高（P < 0.001）。结论：经腹盆腔CT减剂量平扫结合DL后处理技术能保证图像质量，满足诊断需要。
Purpose: To compare image quality and lesion diagnosis between reduced-dose abdominopelvic unenhanced computed tomography (CT) using deep learning (DL) post-processing and standard-dose CT using iterative reconstruction (IR).Method: Totally 251 patients underwent two consecutive abdominopelvic unenhanced CT scans of the same range, including standard and reduced doses, respectively. In group A, standard-dose data were reconstructed by (blend 30 %) IR. In group B, reduced-dose data were reconstructed by filtered back projection reconstruction to obtain group B1 images, and post-processed using the DL algorithm (NeuAI denosing, Neusoft medical, Shenyang, China) with 50 % and 100 % weights to obtain group B2 and B3 images, respectively. Then, CT values of the liver, the second lumbar vertebral centrum, the erector spinae and abdominal subcutaneous fat were measured. CT values, noise levels, signal-to-noise ratios (SNRs), contrast-to-noise ratios (CNRs), radiation doses and subjective scores of image quality were compared. Subjective evaluations of low-density liver lesions were compared by diagnostic results from enhanced CT or Magnetic Resonance Imaging.Results: Groups B3 and B1 showed the lowest and highest noise levels, respectively (P < 0.001). The SNR and CNR in group B3 were highest (P < 0.001). The radiation dose in group B was reduced by 71.5 % on average compared to group A. Subjective scores in groups A and B2 were highest (P < 0.001). Diagnostic sensitivity and confidence for liver metastases in groups A and B2 were highest (P < 0.001).Conclusions: Reduced-dose abdominopelvic unenhanced CT combined with DL post-processing could ensure image quality and satisfy diagnostic needs.