Predisposing Factors for Spontaneous Closure of Congenital Portosystemic Shunts

Predisposing Factors for Spontaneous Closure of Congenital Portosystemic Shunts
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DOI:
10.1016/j.jpeds.2015.06.073
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发表时间:
2015-10-01
影响因子:
5.1
通讯作者:
Alvarez, Fernando
Alvarez, Fernando
中科院分区:
医学2区
文献类型:
--
作者:
Paganelli, Massimiliano;Lipsich, Jose E.;Alvarez, Fernando

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在对382例先天性门系统分流的回顾中,我们发现新生儿胆汁淤积强烈预测肝内分流的自发关闭(OR 8.3, 95% CI 3.4-20.2)。在24月龄前自发关闭远端或多个分流的可能性更大,但对于静脉导管未闭的可能性较小。
In a review of 382 cases of congenital portosystemic shunt, we found that presentation with neonatal cholestasis strongly predicts spontaneous closure of intrahepatic shunts (OR 8.3, 95% CI 3.4-20.2). Spontaneous closure before the 24th month of age is more likely for distal or multiple shunts, but rare for patent ductus venosus.