Shedding light on gibberellic acid signalling.
Shedding light on gibberellic acid signalling.
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DOI：
10.1016/j.pbi.2008.09.004
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发表时间：
2009-02
影响因子：
9.5
通讯作者：
C. Schwechheimer;B. Willige
中科院分区：
文献类型：
--
作者：
C. Schwechheimer;B. Willige
赤霉酸 (GA) 促进植物的一系列发育和生长过程，其中最著名的是发芽、伸长生长和开花时间。 DELLA 阻遏物是该通路的关键角色。它们的存在或通过 26S 蛋白酶体进行的 GA 依赖性周转在很大程度上分别与 GA 依赖性生长反应的抑制或去抑制相关。最近的进展揭示了 DELLA 阻遏物在几种新的反应途径中的作用，并且在生化水平上，它们现已被证明在光调节幼苗发育的背景下可作为 PHYTOCHROME INTERACTING FACTOR3 (PIF3) 和 PIF4 转录激活剂的阻遏物。此外，基于苔藓立碗藓、石松植物卷柏和种子植物之间的比较基因组学，我们对 GA 信号通路的进化有了初步的了解。
Gibberellic acid (GA) promotes a range of developmental and growth processes in plants, the most well-known being germination, elongation growth and flowering time. DELLA repressors are the key players of the pathway. Their presence or their GA-dependent turnover via the 26S proteasome correlates to a large extent with the repression or derepression, respectively, of GA-dependent growth responses. Recent progress has revealed the role of DELLA repressors in several novel response pathways, and at the biochemical level, they have now been shown to function as repressors of the PHYTOCHROME INTERACTING FACTOR3 (PIF3) and PIF4 transcriptional activators in the context of light-regulated seedling development. Furthermore, the first insights have been gained into the evolution of the GA signalling pathway on the basis of comparative genomics between the moss Physcomitrella patens, the lycophyte Selaginella moellendorffii and seed plants.