Effect of black tea drinking on blood lipids, blood pressure and aspects of bowel habit

Effect of black tea drinking on blood lipids, blood pressure and aspects of bowel habit
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DOI:
10.1079/bjn19970117
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发表时间:
1997-07-01
影响因子:
3.6
通讯作者:
Cummings, JH
Cummings, JH
中科院分区:
医学3区
文献类型:
--
作者:
Bingham, SA;Vorster, H;Cummings, JH

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31名男性(47(SD 14)岁)和34名女性(35(SD 13)岁)参加了一项为期4周的随机交叉试验,以比较每天6杯红茶与安慰剂(水,咖啡因,牛奶和糖)对血脂,排便习惯和血压的影响,在导入期和试验期的第2,3和4周结束时进行测量。通过在选定的茶袋中加入已知量的g-氨基苯甲酸(PABA),然后测量其在尿液中的排泄来建立依从性。在导入期、安慰剂和喝茶期间的平均血清胆固醇值分别为5.67(SD 1.05)、5.76(SD 1.11)和5.69(SD 1.09)mmol/l(P = 0.16)。与安慰剂相比,茶干预期间的饮食、LDL-胆固醇、HDL-胆固醇、甘油三酯和血压也没有显著变化。与安慰剂相比,茶使粪便变软(P = 0.04),在排便习惯方面没有发现其他差异,当15名"不依从者",其PABA排泄表明使用了少于六个茶包的人被排除在分析之外,并且对于第一次或第二次给予茶的人,分别考虑了磨合期和茶期之间的差异。
Thirty-one men (47 (SD 14) years) and thirty-four women (35 (SD 13) years) took part in a 4-week randomized cross-over trial to compare the effect of six mugs of black tea daily v. placebo (water, caffeine, milk and sugar) on blood lipids, bowel habit and blood pressure, measured during a run-in period and at the end of weeks 2, 3 and 4 of the test periods. Compliance was established by adding a known amount of g-aminobenzoic acid (PABA) to selected tea bags, and then measuring its excretion in urine, Mean serum cholesterol values during run-in, placebo and on tea drinking were 5.67 (SD 1.05), 5.76 (SD 1.11) and 5.69 (SD 1.09) mmol/l (P = 0.16). There mere also no significant changes in diet, LDL-cholesterol, HDL-cholesterol, triacylglycerols, and blood-pressure in the tea intervention period compared with placebo, Compared with placebo, stool consistency was softened with tea (P = 0.04), and no other differences were found in bowel habit, Results were-unchanged when fifteen 'non-compliers', whose PABA excretion indicated that fewer than six tea bags had been used, were excluded from the analysis, and when differences between run-in and tea periods were considered separately for those who were given tea first or second.