Parcellation of cortical Afferents to three distinct sectors in the Parahippocampal gyrus of the rhesus monkey: An anatomical and neurophysiological study
Parcellation of cortical Afferents to three distinct sectors in the Parahippocampal gyrus of the rhesus monkey: An anatomical and neurophysiological study
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DOI：
10.1002/cne.10866
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发表时间：
2003-11-10
影响因子：
2.5
通讯作者：
Rosene, DL
中科院分区：
文献类型：
--
作者：
Blatt, GJ;Pandya, DN;Rosene, DL
恒河猴海马旁后回（PHG）由三个不同的皮质区域组成，其细胞结构、连接性和神经生理反应特性各不相同。荧光逆行示踪剂放置在每个PHG区域表现出独特的模式，皮质传入输入到TH，TL和TF区。TF区接收来自上级颞沟的多模态皮质（包括PGa、TPO和MST区）、来自视空间顶叶区PG-Opt以及来自视觉区V3 A和背侧V4的输入。TL区接受来自包括视觉区TE 1和TE 2的颞下区以及来自上级颞沟的下岸和深度中的TEa、IPa和FST区的传入。相反，对TH区的输入来自上级颞回的吻侧部分，包括听觉联合区TS 1 -3，以及来自上级颞沟中TPO区的中间部分。额叶和扣带回区也以很大程度上不同的模式投射到PHG。为了进一步研究这一点，相关的电生理研究的三个PHG领域的确认，这些差异的皮质输入，如视觉反应神经元被发现在TF和TL区，听觉反应神经元或双峰听觉/视觉反应神经元的TH区，和躯体感觉反应神经元在TF/TL边界。由于每个PHG区域也接收不同的海马输入，这些数据表明，单峰或多峰信息的处理可能与记忆处理功能有关，这些功能在很大程度上被隔离在TH，TL和TF区域内。(C)2003 Wiley-Liss，Inc.
The posterior parahippocampal gyrus (PHG) of the rhesus monkey (Macaca mulatta) is comprised of three distinct cortical areas based on cytoarchitecture, connectivity, and neurophysiological response properties. Fluorescent retrograde tracers placed in each PHG area demonstrated unique patterns of cortical afferent input to areas TH, TL, and TF. Area TF receives inputs from the multimodal cortices of the superior temporal sulcus including areas PGa, TPO, and MST, from the visuospatial parietal area PG-Opt, and from visual areas V3A and dorsal V4. Area TL receives afferents from the inferotemporal region including visual areas TE1 and TE2 as well as from areas TEa, IPa, and FST in the lower bank and depth of the superior temporal sulcus. In contrast, the input to area TH is from the rostral part of superior temporal gyrus, including the auditory association areas TS1-3, and from the middle sector of area TPO in the superior temporal sulcus. Frontal and cingulate areas also project to the PHG in largely differential patterns. To further investigate this a correlative electrophysiological study of the three PHG areas resulted in a confirmation of these differential cortical inputs such that visually responsive neurons were found in areas TF and TL, auditory responsive neurons or bimodal auditory/visual-responsive neurons in area TH, and somatosensory-responsive neurons at the TF/TL border. Since each PHG area also receives differential hippocampal input, these data suggest that the processing of unimodal or multimodal information may be related to memory processing functions that are largely segregated within areas TH, TL, and TF. (C) 2003 Wiley-Liss, Inc.