Outbreak of Zika virus disease in the Americas and the association with microcephaly, congenital malformations and Guillain-Barré syndrome.
Outbreak of Zika virus disease in the Americas and the association with microcephaly, congenital malformations and Guillain-Barré syndrome.
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DOI：
10.1136/archdischild-2016-310590
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发表时间：
2016-07
影响因子：
5.2
通讯作者：
Morgan D
中科院分区：
文献类型：
--
作者：
Ladhani SN;O'Connor C;Kirkbride H;Brooks T;Morgan D
在2007年之前，寨卡病毒（ZIKV）通常被认为是一种重要性有限的虫媒病毒，在热带非洲和东南亚引起轻度自限性发热疾病。现在，2015年初在巴西开始的ZIKV大规模持续爆发正在美洲迅速蔓延，并可能与先天性畸形（包括小头畸形）和格林-巴利综合征（GBS）有关。在英格兰，截至2016年2月4日，五名成年人在前往目前正在经历ZIKV疫情的国家旅行后被诊断出患有ZIKV感染。
Prior to 2007, Zika virus (ZIKV) was generally considered an arbovirus of limited importance, causing a mild self-limiting febrile illness in tropical Africa and Southeast Asia. Now, a large, ongoing outbreak of ZIKV that started in Brazil in early 2015 is spreading rapidly across the Americas and has been potentially linked to congenital malformations (including microcephaly) and Guillain–Barré syndrome (GBS). In England, as of 4 February 2016, five adults have been diagnosed with ZIKV infection following travel to countries currently experiencing a ZIKV outbreak.