Study on Thermal Stress in Living Tissues during Cryosurgical Re-warming
Study on Thermal Stress in Living Tissues during Cryosurgical Re-warming
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发表时间：
2002
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通讯作者：
Zhang Yan
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作者：
Zhang Yan
目的研究冷冻外科三区复温过程中的热应力发展。方法以水、马铃薯、猪肝为实验材料，直接观察其在特定的冷冻、复温或两者混合过程中产生的裂纹。采用变时间步长隐式有限差分法计算了三区解冻过程中组织温度场和热应力场。结果获得了复温过程中组织表面的瞬态热应力场，并与单纯冷冻过程中的应力场进行了比较，发现复温过程中组织表面的应力分布与单纯冷冻过程中的应力分布方向相反.结论冷冻后立即快速复温可能比单纯冷冻引起更大的裂纹.这可能在冷冻外科中具有重要价值。
Objective To examine the thermal stress development during cryosurgical three region re warming. Method Several samples such as water, potato and pork liver were utilized to directly observe the crack developed inside them when subjected to a specific freezing or rewarming or a mixed procedure between them. The implicit finite difference method with variable time step was applied to calculate the tissue temperature and the thermal stress fields induced in three region thawing process. Result The transient thermal stress field over the tissue during re warming was obtained and results were compared with that in a simple freezing process.It was found that the stress distributions during the thawing stage are in opposite direction with those of the freezing process.Conclusion Quick re warming immediately following cryosurgical freezing may induce much stronger crack than using only a simple freezing treatment. This may have important value in cryosurgery.