Familial hypertrophic cardiomyopathy - Cardiac ultrasonic abnormalities in genetically affected subjects without echocardiographic evidence of left ventricular hypertrophy
Familial hypertrophic cardiomyopathy - Cardiac ultrasonic abnormalities in genetically affected subjects without echocardiographic evidence of left ventricular hypertrophy
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DOI：
10.1053/euhj.1997.0735
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发表时间：
1998-03-01
影响因子：
39.3
通讯作者：
Komajda, M
中科院分区：
文献类型：
--
作者：
Hagege, AA;Dubourg, O;Komajda, M
Aims It is not known whether the apparent normality of echocardiographic examination results, in subjects bearing a mutation for hypertrophic cardiomyopathy but without ultrasonic left ventricular hypertrophy, is due to incomplete phenotypic expression, or inaccurate echocardiographic criteria. The aim of this study was to search for echocardiographic abnormalities in these patients.Methods and Results Echocardiography was performed in 100 subjects from two families with a mutation in the beta-MHC (720) or My-BPC (714) genes. We compared genetically affected subjects with an apparently normal left ventricle (thickness
