Giant magnetoimpedance biosensor for ferrogel detection: Model system to evaluate properties of natural tissue
Giant magnetoimpedance biosensor for ferrogel detection: Model system to evaluate properties of natural tissue
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DOI：
10.1063/1.4921224
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发表时间：
2015-05-11
影响因子：
4
通讯作者：
Blyakhman, F. A.
中科院分区：
文献类型：
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作者：
Kurlyandskaya, G. V.;Fernandez, E.;Blyakhman, F. A.
采用薄膜磁阻抗（MI）传感器定量测定铁凝胶中磁性纳米颗粒（MNPs）的浓度。在激光靶蒸发法制备的γ - fe2o3 MNPs水悬浮液中，用丙烯酰胺自由基聚合法制备了铁凝胶（生物组织模型体系）。采用溅射法制备了MI [FeNi/Ti](3)/Cu/[Ti/FeNi](3)/Ti敏感元件。对MNPs、铁凝胶和多层敏感元件进行了深入的结构和磁性研究，确保了生物传感器原型的完整表征。在初始状态和不同氧化铁MNPs浓度（从0到2.44 wt. %）的铁凝胶存在下，仔细评估了敏感元件的MI响应，这在300 kHz至400 MHz的频率范围内产生了MI的系统变化。(C) 2015 AIP出版有限责任公司
Thin-film based magnetoimpedance (MI) sensors were used for quantitative determination of the concentration of magnetic nanoparticles (MNPs) in ferrogels. Ferrogels (model systems for biological tissue) were synthesized by radical polymerization of acrylamide in a stable aqueous suspension of gamma-Fe2O3 MNPs fabricated by laser target evaporation. MI [FeNi/Ti](3)/Cu/[Ti/FeNi](3)/Ti sensitive elements were prepared by sputtering. Thorough structural and magnetic studies of MNPs, ferrogels, and multilayered sensitive element insure the complete characterization of biosensor prototype. The MI response of the sensitive element was carefully evaluated in initial state and in the presence of ferrogels with different concentration of iron oxide MNPs from 0 to 2.44 wt. %, which produced systematic changes of the MI in a frequency span of 300 kHz to 400 MHz. (C) 2015 AIP Publishing LLC.