The influence of virus structure on antibody responses and virus serotype formation
The influence of virus structure on antibody responses and virus serotype formation
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DOI：
10.1016/s0167-5699(96)10066-9
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发表时间：
1996-12-01
期刊：
影响因子：
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通讯作者：
Zinkernagel, RM
中科院分区：
文献类型：
--
作者：
Bachmann, MF;Zinkernagel, RM
抗体在保护免受一些原发性和大多数继发性病毒感染方面很重要。然而，病毒与免疫系统共同进化，可能已经适应了宿主的抗体反应，在某些情况下甚至可能破坏它。在这里，Martin Bachmann和Rolf Zinkernagel总结了B细胞使用病毒表面抗原的重复性作为外来性标记的证据，这在宿主-病毒关系的进化中起着重要作用。
Antibodies are important in protection against some primary and most secondary viral infections. However, viruses have co-evolved with the immune system and might have adapted to the host's antibody response and in some cases might even subvert it. Here, Martin Bachmann and Rolf Zinkernagel summarize evidence that B cells use repetitiveness of viral surface antigens as a marker for foreignness, which plays an important role in the evolution of host-viral relationships.