Multitaper Analysis of Semi-Stationary Spectra From Multivariate Neuronal Spiking Observations

Multitaper Analysis of Semi-Stationary Spectra From Multivariate Neuronal Spiking Observations
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多变量神经元尖峰观察的半稳态光谱的多锥度分析

DOI:
10.1109/tsp.2020.3010197
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发表时间:
2020
影响因子:
5.4
通讯作者:
Babadi, Behtash
Babadi, Behtash
中科院分区:
工程技术1区
文献类型:
--
作者:
Rupasinghe, Anuththara;Babadi, Behtash

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提取神经过程的频谱表征是理解大脑节律如何调节认知功能的关键。虽然连续时间序列的光谱估计已经得到了很好的研究,但基于峰值观测推断潜在非平稳过程的光谱表示是具有挑战性的,因为潜在的非线性限制了现有方法的光谱时间分辨率。在本文中,我们通过开发一种多锥度光谱估计方法来解决这个问题,该方法可以直接应用于多变量峰值观测,以提取控制峰值活动的潜在非平稳过程的半平稳光谱密度。我们建立了我们所提出的估计量的偏方差权衡的理论界限。最后,我们提出的技术在模拟和真实数据中的应用表明,与现有方法相比,性能有了显著提高。
Extracting the spectral representations of neural processes that underlie spiking activity is key to understanding how brain rhythms mediate cognitive functions. While spectral estimation of continuous time-series is well studied, inferring the spectral representation of latent non-stationary processes based on spiking observations is challenging due to the underlying nonlinearities that limit the spectrotemporal resolution of existing methods. In this paper, we address this issue by developing a multitaper spectral estimation methodology that can be directly applied to multivariate spiking observations in order to extract the semi-stationary spectral density of the latent non-stationary processes that govern spiking activity. We establish theoretical bounds on the bias-variance trade-off of our proposed estimator. Finally, application of our proposed technique to simulated and real data reveals significant performance gains over existing methods.
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