A Life Cycle for Modeling Biology at Different Scales.

A Life Cycle for Modeling Biology at Different Scales.
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DOI:
10.3389/fpls.2021.710590
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发表时间:
2021
影响因子:
5.6
通讯作者:
Roeder AHK
Roeder AHK
中科院分区:
生物学2区
文献类型:
--
作者:
Harline K;Martínez-Gómez J;Specht CD;Roeder AHK

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Modeling has become a popular tool for inquiry and discovery across biological disciplines. Models allow biologists to probe complex questions and to guide experimentation. Modeling literacy among biologists, however, has not always kept pace with the rise in popularity of these techniques and the relevant advances in modeling theory. The result is a lack of understanding that inhibits communication and ultimately, progress in data gathering and analysis. In an effort to help bridge this gap, we present a blueprint that will empower biologists to interrogate and apply models in their field. We demonstrate the applicability of this blueprint in two case studies from distinct subdisciplines of biology; developmental-biomechanics and evolutionary biology. The models used in these fields vary from summarizing dynamical mechanisms to making statistical inferences, demonstrating the breadth of the utility of models to explore biological phenomena.
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