Kidney Transplantation in a Child with Posterior Urethral Valve from a Hepatitis B Virus-Carrier Mother
Kidney Transplantation in a Child with Posterior Urethral Valve from a Hepatitis B Virus-Carrier Mother
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乙型肝炎病毒携带者母亲患有后尿道瓣膜的儿童的肾移植
DOI：
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发表时间：
1999
影响因子：
1.6
通讯作者：
Kouichi Kanagawa
中科院分区：
文献类型：
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作者：
T. Seki;T. Koyanagi;K. Nonomura;T. Yamashita;T. Chikaraishi;Kouichi Kanagawa
本文报告一位七岁男童因后尿道瓣膜症而接受肾脏移植治疗。他需要复杂的重建手术治疗PUV相关疾病，也需要特定的血清学准备B型肝炎（HB），因为他的活体供体母亲是一个被证明的携带者。通过仔细执行重建手术的原则和良好的计划血清免疫学准备，我们已经证明，成功的肾移植可以从一个HB Ag阳性的母亲到一个HB Ag和HB Ab阴性的儿子，即使他的泌尿道是由于PUV严重功能障碍。
The case of a 7-year-old boy with posterior urethral valve (PUV) who underwent successful kidney transplantation for progressive renal failure is reported. He required complex reconstructive surgery for PUV-related disorders, and also specific serological preparation for hepatitis B (HB) as his living donor mother was a proven carrier. By carefully executing the principles of reconstructive surgery and with well-planned seroimmunological preparation, we have demonstrated that successful kidney transplantation can be done from an HB Ag-positive mother to an HB Ag- and HB Ab-negative son, even when his urinary tract is severely dysfunctional due to PUV.