Epidemiology of travel-associated pandemic (H1N1) 2009 infection in 116 patients, Singapore.
Epidemiology of travel-associated pandemic (H1N1) 2009 infection in 116 patients, Singapore.
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DOI：
10.3201/eid1601.091376
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发表时间：
2010-01
影响因子：
11.8
通讯作者：
Cheng Chen MI
中科院分区：
文献类型：
--
作者：
Mukherjee P;Lim PL;Chow A;Barkham T;Seow E;Win MK;Chua A;Leo YS;Cheng Chen MI
在遏制阶段，输入性感染的暴露区域迅速变化。 2009 年 6 月，在新加坡大流行性流感计划遏制阶段，2009 年 H1N1 流感大流行通过输入病例传入该国。为了了解旅行模式如何影响最初的疫情爆发，我们检查了新加坡陈笃生医院收治的首批 116 名患有旅行相关感染的患者的流行病学和旅行数据。 61% 和 54% 的患者分别符合美国疾病控制与预防中心和世界卫生组织针对流感样疾病的体温标准。四分之一的病例发病后曾外出旅行，15%的病例在旅行中患病。输入性感染的暴露区域变化迅速；病例最初来自北美，其次是澳大利亚和东南亚。搭乘长途航班的病例患者在抵达前患病的可能性更大；那些乘坐较短航班的人往往会在抵达后生病。热扫描仪检测到 12% 到达的病例患者发烧，从而缩短了隔离时间。
During the containment phase, regions of exposure for imported infections changed rapidly. In June 2009, during Singapore’s pandemic influenza plan containment phase, pandemic (H1N1) 2009 was introduced into the country through imported cases. To understand how travel patterns affected the initial outbreak, we examined epidemiologic and travel data for the first 116 case-patients admitted to Tan Tock Seng Hospital, Singapore, with travel-associated infection. Sixty-one percent and 54% of patients, respectively, met US Centers for Disease Control and Prevention and World Health Organization temperature criteria for influenza-like illness. One fourth of the case-patients traveled after illness onset, and 15% became ill while traveling. Regions of exposure for imported infections changed rapidly; case-patients initially arrived from North America, followed by Australasia and Southeast Asia. Case-patients on longer flights were more likely to become ill before arrival; those with shorter flights tended to become ill after arrival. Thermal scanners detected fevers in 12% of the arriving case-patients, resulting in a shorter time to isolation.