.gamma.-Cyclodextrin template method for controlling stereochemistry of bimolecular interactions and reactions
.gamma.-Cyclodextrin template method for controlling stereochemistry of bimolecular interactions and reactions
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用于控制双分子相互作用和反应立体化学的γ-环糊精模板方法
DOI：
10.1021/ja00018a051
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发表时间：
1991
影响因子：
15
通讯作者：
S. Nozoe
中科院分区：
文献类型：
--
作者：
A. Ueno;F. Moriwaki;Yoshiko Iwama;Iwao Suzuki;T. Osa;T. Ohta;S. Nozoe
Cl（1）的暴露侧与相邻四聚体的两个水分子和两个NH_2基团形成氢键，而Cl（2）则与四个沃茨形成氢键。溶剂化的氯阴离子Cl（3）和另外两个水分子作为相邻四聚体之间的氢键间隔物。硝酸根的结构是相似的，硝酸根离子楔入相对的嘧啶环之间，N（3）和O（31）原子位于2重轴上。这个客体硝酸根离子与两个四聚体相互作用，一个在上面，一个在下面。客体和主体之间最紧密的接触发生在中心氧原子O（31）和“较低”环的两个C（6）质子之间：O-（31）-C（6）3.3 A，O（31）-H（16）2.5 A，O（31）-H（6）-C（6）角= 142。O（32）侧氧与环外N（41 ′）形成3.4 A的静电接触。同样的硝酸盐作为
exposed side of Cl (l) is hydrogen-bonded to two water molecules and two NH2 groups of neighboringtetramers, while Cl (2) is hydrogen-bonded to four waters. A solvated chloride anion Cl (3) and the other two water molecules act as hydrogen-bonding spacers between neighboring tetramers. The nitrate structure is similar, with a nitrate ion wedged between opposite pyrimidinium rings, with the N (3) and 0 (31) atoms located on the 2-fold axis. This guest nitrate ion interacts with two tetramers, one above and one below. The closest contact between guest and host occurs between the central oxygen atom, 0 (31), and both of the C (6) protons of the “lower” rings: O-(31)-C (6) 3.3 A, 0 (31)-H (16) 2.5 A, 0 (31)-H (6)-C (6) angle= 142. The 0 (32) lateral oxygens form electrostatic contacts of 3.4 A with the exocyclic N (41'). The same nitrate acts as a