3-Hydroxy fatty acids found in capsules of Cryptococcus neoformans

3-Hydroxy fatty acids found in capsules of Cryptococcus neoformans
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DOI:
10.1139/w07-045
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发表时间:
2007-06-01
影响因子:
2.8
通讯作者:
Kock, Johan L. F.
Kock, Johan L. F.
中科院分区:
生物学4区
文献类型:
--
作者:
Sebolai, Olihile M.;Pohl, Carolina H.;Kock, Johan L. F.

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利用免疫荧光共聚焦激光扫描显微镜、免疫金透射电子显微镜和气相色谱-质谱联用技术,我们证明了新型隐球菌中3-羟基脂肪酸的存在。我们的研究结果表明,这些氧脂素积聚在胶囊中,在胶囊中它们作为疏水性液滴通过管状突起释放到周围介质中。
Using immunofluorescence confocal laser scanning microscopy, immunogold transmission electron microscopy and gas chromatography - mass spectrometry, we demonstrated the presence of 3-hydroxy fatty acids in Cryptococcus neoformans. Our results suggest that these oxylipins accumulate in capsules where they are released as hydrophobic droplets through tubular protuberances into the surrounding medium.