Immune response to Blomia kulagini and Dermatophagoides pteronyssinus in Sweden and Brazil.

Immune response to Blomia kulagini and Dermatophagoides pteronyssinus in Sweden and Brazil.
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瑞典和巴西对库拉吉尼布洛米亚 (Blomia kulagini) 和屋尘螨 (Dermatophagoides pteronyssinus) 的免疫反应。

DOI:
10.1159/000235113
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发表时间:
1990
期刊:
International archives of allergy and applied immunology
影响因子:
--
通讯作者:
S. Johansson
S. Johansson
中科院分区:
--
文献类型:
--
作者:
M. van Hage;L. Machado;M. Barros;S. Johansson

文献摘要

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非pyroglyphid螨Blomia kulagini和pyroglyphid螨屋尘螨的免疫反应进行了比较,在440名瑞典农民和34名过敏性受试者从巴西使用放射性过敏吸附试验(RAST)。都是B。kulagini和D.屋尘螨是致敏的常见原因,特别是在巴西。RAST评分最高的是D.在这两个国家的血清中发现了屋尘螨。用RAST抑制技术研究了两种螨之间的变应原交叉反应性。都是B。kulagini和D.屋尘螨具有它们自己独特的过敏原以及共同的过敏原。因此,在开始脱敏治疗之前,除了属于Dermatophagoides属的螨外,还应考虑不同国家的其他pyroglyphid和非pyroglyphid螨。
The immune responses to the non-pyroglyphid mite Blomia kulagini and the pyroglyphid mite Dermatophagoides pteronyssinus were compared in 440 Swedish farmers and 34 allergic subjects from Brazil using the radioallergosorbent test (RAST). Both B. kulagini and D. pteronyssinus were shown to be a common cause of sensitization, particularly in Brazil. The highest RAST scores were found against D. pteronyssinus in sera from both countries. Allergenic cross-reactivity between the two mites was studied by the RAST inhibition technique. Both B. kulagini and D. pteronyssinus possess their own unique allergens as well as allergens in common. Thus, besides mites belonging to the Dermatophagoides genus, other pyroglyphid and non-pyroglyphid mites in different countries should be taken into consideration before starting hyposensitization treatments.