Unilateral clubbing of fingers associated with causalgia.
Unilateral clubbing of fingers associated with causalgia.
复制标题
单侧杵状指伴有灼痛。
DOI：
10.1136/bmj.297.6664.1635-b
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发表时间：
1988
影响因子：
--
通讯作者：
M. Hanna
中科院分区：
文献类型：
--
作者：
P. Saunders;M. Hanna
一名 24 岁女性出现皮肤橙黄色变色，最明显的是手掌和脚底。膳食评估显示，她每天摄入的胡萝卜素总量为9200克，其中一半以上来自番茄汤；正常每日摄入量900-1200焦克。她的血清胡萝卜素浓度升至67-jmol/l；她的血清视黄醇（维生素 A）浓度正常为 1·1 μmol/l。过量摄入含有胡萝卜素的食物会导致高胡萝卜素血症导致的皮肤色素异常沉着。如果这种食物是胡萝卜，则可能会发现血清维生素A和胡萝卜素浓度升高。番茄中的主要类胡萝卜素是番茄红素，它不具有维生素原 A 活性。这解释了女性血清维生素 A 浓度正常的原因。她减少了番茄汤的摄入量，六个月后，她的皮肤变色程度减轻了。
A 24 year old woman presented with orange-yellow discoloration of her skin, most noticeable on her paLms and soles. Dietary assessment showed that her total daily intake of carotene was 9200 Rg, over half of which came from tomato soup; normal daily intake 900-1200 jg. Her serum carotene concentration was raisedat 67-jmol/l; her serum retinol (vitamin A) con-centration was normal at 1 1 jImol/l. Abnormal pigmentation of the skin due to hypercarotenaemia occurs with an excessivedietary intake of food that contains carotene. If this food is carrots raised serum vitamin A and carotene concentrations may be found. The predominant-carotenoid in tomatoes is lycopene, which does not possess provitamin A activity. This explains the woman's normal serum vitamin A concentration. She reduced her consumption of tomato soup, and six months later her skin was less discoloured.