VIEgram – Analysis and Visualization of Intracardiac Electrograms on Patient-Specific 3D Atria Model

VIEgram – Analysis and Visualization of Intracardiac Electrograms on Patient-Specific 3D Atria Model
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VIEgram — 患者特定 3D 心房模型上心内电图的分析和可视化

DOI:
10.1109/embc44109.2020.9175917
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发表时间:
2020
期刊:
IEEE EMBS
影响因子:
--
通讯作者:
Tolkacheva, Elena G.
Tolkacheva, Elena G.
中科院分区:
--
文献类型:
--
作者:
Thakare, Sanket;Mulpuru, Siva K.;Roukoz, Henri;Tolkacheva, Elena G.

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在过去几年中,心脏标测用于心律失常的有效诊断和治疗的使用显著增加。在临床环境中,电解剖标测(EAM)在电生理手术期间使用专有系统(如CARTO、EnSite Precision、RHYTHMIA等)进行。这些系统生成具有电活动的患者特定心房的3D模型(即,心内电描记图(iEGM)),用于进一步识别心律失常的来源和指导心脏消融治疗。最近,开发了几种新的技术来进行iEGMs分析,以更准确地识别致瘤位点。然而,由于其专有限制,将iEGMs分析的结果结合回EAM系统存在困难。这在进一步开发新技术以帮助导航患者特异性临床消融治疗方面造成了障碍。因此,我们开发了一个开源软件VIEgram1,允许研究人员在患者特定的3D心房模型上可视化各种iEGM分析的结果。它消除了学术环境对专有EAM系统的依赖,从而使追溯映射过程非常方便和省时。在这里,我们展示了VIEgram的功能,如iEGMs的视觉检查,在实现自定义iEGMs分析技术和插值方案,空间分析的灵活性。
Over the last few years, the use of cardiac mapping for effective diagnosis and treatment of arrhythmias has increased significantly. In the clinical environment, electroanatomical mapping (EAM) is performed during the electrophysiological procedures using proprietary systems such as CARTO, EnSite Precision, RHYTHMIA, etc. These systems generate the 3D model of patient-specific atria with the electrical activity (i.e., intracardiac electrograms (iEGMs)) displayed on it, for further identification of the sources of arrhythmia and for guiding cardiac ablation therapy. Recently, several novel techniques were developed to perform iEGMs analysis to more accurately identify the arrhythmogenic sites. However, there is a difficulty in incorporating the results of iEGMs analysis back to EAM systems due to their proprietary constraints. This created a hurdle in the further development of novel techniques to help navigate patient-specific clinical ablation therapy. Thus, we developed an open source software, VIEgram1, that allows researchers to visualize the results of the various iEGMs analysis on a patient-specific 3D atria model. It eliminates the dependency of the academic environment on the proprietary EAM systems, thereby making the process of retrospective mapping extremely convenient and time efficient. Here, we demonstrate the features of VIEgram such as visual inspection of iEGMs, flexibility in implementing custom iEGMs analysis techniques and interpolation schemes, and spatial analysis.
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