Numerical study on high intensity focused ultrasound therapy using array transducer
Numerical study on high intensity focused ultrasound therapy using array transducer
复制标题
阵列换能器高强度聚焦超声治疗的数值研究
DOI：
10.1016/j.phpro.2010.01.042
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Y. Matsumoto
中科院分区：
文献类型：
--
作者：
K. Okita;K. Sugiyama;K. Ono;S. Takagi;Y. Matsumoto
HIFU治疗肝癌、脑癌等深部肿瘤的发展一直是人们所期待的。其中一个问题是由于超声波的反射和折射引起焦点的位移。在本研究中，HIFU治疗脑癌通过颅骨与碗状阵列换能器进行数值。我们的方法是用介质状态方程来求解混合物的质量和动量方程。非线性主要通过介质的状态方程来考虑。研究了具有相位延迟的阵列换能器对焦点的三维可控性。由于有相位延迟的超声通过颅骨传播，我们获得了一个清晰的焦点，其峰值压力高于没有相位延迟的峰值压力。因此，具有适当相位延迟的阵列换能器能够充分地将焦点分配到目标上，即使超声波通过非均匀介质（如人类头骨）传播。
The development of the HIFU therapy for the deeply placed cancer such as the liver cancer and brain cancer has been desired. One problem is the displacement of the focal point due to the reflection and refraction of ultrasound. In the present study, the HIFU therapy for the brain cancer through a skull with a bowl-shape array transducer is performed numerically. Our approach is to solve the mass and momentum equations for mixture with the equation of state of media. The nonlinearity is mainly taken into account through the equation of state of the media. The three-dimensional controllability of the focal point by the array transducer with a phase delay is examined. As the result of the ultrasound propagation through the skull with the phase delay, we obtain a clear focal point where the peak pressure is higher than that without the phase delay. Therefore, the array transducer with the appropriate phase delay enables to assign the focal point to the target adequately, even if the ultrasound propagates through the inhomogeneous medium as a human skull.
影响因子：
4.1
作者：
BERENGER, JP
通讯作者：
BERENGER, JP