Seasonal pattern of spontaneous cervical artery dissection
Seasonal pattern of spontaneous cervical artery dissection
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DOI：
10.3171/jns.1998.89.1.0101
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发表时间：
1998-07-01
影响因子：
4.1
通讯作者：
Kuiper, JD
中科院分区：
文献类型：
--
作者：
Schievink, WI;Wijdicks, EFM;Kuiper, JD
Object.自发性颈动脉夹层的病因尚不清楚，但可能涉及遗传和环境因素。本研究的目的是确定自发性颈动脉夹层是否存在季节性。自发性颈动脉夹层的季节性模式进行了分析，在一组连续的200例患者（104名女性和96名男性，平均年龄为44.9岁），使用瑞利测试在1970年至1990年期间进行了评估。大多数患者居住在美国中西部地区，那里的气候季节性波动很大。自发性颈动脉夹层的发生率呈年周期性变化，10月为高峰期（P < 0.02）。季节性变化很大，秋季颈动脉夹层患者比其他季节多约53%。自发性颈动脉夹层存在季节性模式，高峰出现在10月。季节性的原因仍有待解释;然而，天气或传染病相关因素可能提供病原学线索。
Object. The etiology of spontaneous cervical artery dissection is poorly understood; however, it may involve genetic and environmental factors. The purpose of this study was to determine whether seasonality of spontaneous cervical artery dissection exists.Methods. The seasonal pattern of spontaneous cervical artery dissection was analyzed in a group of 200 consecutive patients (104 females and 96 males with a mean age of 44.9 years) who were evaluated using the Rayleigh test during the period from 1970 to 1990. The majority of patients resided in the midwestern section of the United States, where large seasonal fluctuations in climate occur. A circannual periodicity was found in the frequency of spontaneous cervical artery dissections with a peak occurring in October (p < 0.02). The seasonal variation was substantial, with approximately 53% more patients suffering a cervical artery dissection during autumn than during other seasons.Conclusions. A seasonal pattern of' spontaneous cervical artery dissection exists with a peak occurring in October. The cause of the seasonality remains to be explained; however, weather- or infectious disease-related factors may pro vide etiological leads.