Repeatability of heart rate variability during simple cardiovascular reflex tests on healthy subjects

Repeatability of heart rate variability during simple cardiovascular reflex tests on healthy subjects
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DOI:
10.1016/s0188-4409(00)00255-1
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发表时间:
2001-01-01
影响因子:
7.7
通讯作者:
Cárdenas, M
Cárdenas, M
中科院分区:
医学4区
文献类型:
--
作者:
Jáuregui-Renaud, K;Hermosillo, AG;Cárdenas, M

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背景我们的目的是确定重复性,2周后,在简单的心血管反射试验,方法心率变异性(HRV)的频域措施。对20名年龄为29.3 ± 2.5岁的健康志愿者进行了两次评估分别于第0周和第2周记录自主呼吸和节拍器起搏呼吸时的连续心电图和每分钟血压(0.2 Hz),在起搏呼吸下,进行两项测试:1)主动改变姿势:冷压试验:将右手浸入5 ℃冷水中2 min。起搏呼吸引起心率变异性(HRV)的高频(HF)分量显著增加,这种效应在95%的受试者中可重复。主动改变体位可使心率显著增加,心率变异性的低频/高频比值增大。虽然坐着的反应的重复性比站着的反应好,但它总是高于90%。冷压试验引起心率和血压显著增加,但HRV测量值变化不定(降低或升高)。95-100%的受试者的应答重复性明显。虽然同一受试者的HRV测量重复性高于95%,但重复性系数反映了受试者之间的较大差异。结果表明,这是不可取的,使用孤立的HRV变化来解释简单的心血管反射测试在健康受试者群体的反应。(C)2001 IMSS,由Elsevier Science Inc.出版。
Background. Our purpose was to determine the repeatability, after 2 weeks, of frequency domain measures of heart rate variability (HRV) during simple cardiovascular reflex tests,Methods. Twenty healthy volunteers aged 29.3 +/- 2.5 years were assessed twice (at weeks 0 and 2), Continuous electrocardiogram and minute-to-minute blood pressure were recorded during spontaneous and metronome-paced breathing (0.2 Hz), Under paced breathing, two tests were performed: 1) active change of posture: 5 min supine position, 5 min seated upright, and 5 min standing up, and 2) cold presser test: the right hand was immersed in cold water (5 degreesC) for 2 min.Results. Paced breathing elicited a significant increase of the high-frequency (HF) component of HRV, This effect was repeatable on 95% of the subjects. Active change of posture induced a significant increase of the heart rate with an increase of the low-frequency/high-frequency ratio of HRV. Although repeatability was better for the response to being seated upright than for the response to being standing up, it was always higher than 90%. The cold presser test induced a significant increase of the heart rate and blood pressure, but with variable changes on the HRV measurements (either a decrease or an increase). Repeatability of responses was evident for 95-100% of the subjects. Although repeatability of HRV measurements in the same subject during the tests was higher than 95%, coefficients of repeatability reflected large differences among the subjectsConclusions. The results suggest that it is not advisable to use isolated HRV changes to interpret the response to simple cardiovascular reflex tests in groups of healthy subjects. (C) 2001 IMSS, Published by Elsevier Science Inc.