Transcriptome Comparison of Brain and Kidney Endothelial Cells in Homeostasis.
Transcriptome Comparison of Brain and Kidney Endothelial Cells in Homeostasis.
复制标题
脑和肾内皮细胞稳态的转录组比较
DOI：
10.1155/2022/5239255
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发表时间：
2022
影响因子：
--
通讯作者：
Jian C
中科院分区：
文献类型：
--
作者：
Huang X;Huang Z;Wei Z;Feng Y;Li X;Xu A;Jian C
Endothelial cells are heterogeneous, stemming from multiple organs, but there is still little known about the connection between the brain and kidney endothelial cells, especially in homeostasis. In this study, scRNA-seq results were obtained to compare genetic profiles and biological features of tissue-specific endothelial cells. On this basis, seven endothelial cell subpopulations were identified, two of which were upregulated genes in pathways related to stroke and/or depression, as characterized by neuroinflammation. This study revealed the similarities and distinctions between brain and kidney endothelial cells, providing baseline information needed to fully understand the relationship between renal diseases and neuroinflammation, such as stroke and depression.
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
Kondybayeva, Aida;Akimniyazova, Aigul;Ivashchenko, Anatoliy
通讯作者：
Ivashchenko, Anatoliy
影响因子：
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通讯作者：
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DOI：
10.12659/msm.893531
发表时间：
2015-06-23
期刊：
Medical science monitor : international medical journal of experimental and clinical research
影响因子：
--
作者：
Shi H;Feng G;Wang Z;Zhou C;Zhong G;Hu Y;Wang G
通讯作者：
Wang G