Marijuana and T Iymphocyte rosettes
Marijuana and T Iymphocyte rosettes
复制标题
大麻和 T 淋巴细胞玫瑰花结
DOI：
10.1002/cpt1976193310
复制
发表时间：
1976
影响因子：
6.7
通讯作者：
R. Khurana
中科院分区：
文献类型：
--
作者：
P. Cushman;R. Khurana
在体外研究了吸食大麻对早期（活性）和总T淋巴细胞的绵羊细胞玫瑰花结特性的影响。与34名对照组相比，35名似乎是慢性大麻吸烟者的T细胞形成的活性roximab显着减少。吸烟者和非吸烟者形成的晚期或冷增强的花环是相似的，这表明吸烟者外周血中存在相似数量的花环形成T细胞。这些数据表明，吸食大麻可能会影响T淋巴细胞亚群的功能，通过它们形成早期玫瑰花结的能力来识别，可能是通过影响这些细胞膜。
The effect of marijuana smoking on sheep cell rosetting properties of both early (active) and total T lymphocytes was studied in vitro. Significantly fewer active rosettes were formed by T cells from a population of 35 who appeared to be chronic marijuana smokers than the 34 controls. The late, or cold‐enhanced rosettes formed by smokers and nonsmokers were similar, suggesting that similar numbers of rosette‐forming T cells were present in the peripheral blood of smokers. These data suggest that marijuana smoking may affect the function of a subpopulation of T lymphocytes, identified by their capacity to form early rosettes, possibly by affecting these cell membranes.