Contralateral neglect induced by right posterior parietal rTMS in healthy subjects

Contralateral neglect induced by right posterior parietal rTMS in healthy subjects
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DOI:
10.1097/00001756-200005150-00030
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发表时间:
2000-05-15
期刊:
影响因子:
1.7
通讯作者:
Bisiach, E
Bisiach, E
中科院分区:
医学4区
文献类型:
--
作者:
Fierro, B;Brighina, F;Bisiach, E

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我们应用重复经颅磁刺激(RTMS)对11名健康受试者进行视觉空间知觉干扰。受试者完成一项视觉空间任务,要求判断预想直线的对称性。视觉刺激由对称性或非对称性横断线组成,在计算机监视器上快速呈现50ms。在基础状态下和在rTMS序列中检测10个刺激,频率为25 Hz,通过一个焦点线圈传递到右侧或左侧后顶叶皮质(P5和P6部位),并与视觉刺激同步触发。随机混合的假rTMS列车用于非特异性效应的对照。与基础和假rTMS条件相比,右侧顶叶rtms在对称性判断中引起显著的右倾。其他情况之间没有出现差异。《神经报告》11:1519-1521(C)2000 Lippincott Williams&Wilkins.
We applied repetitive transcranial magnetic stimulation (rTMS) in order to induce interference on visuo-spatial perception in 11 healthy subjects. Subjects performed a visuo-spatial task requiring judgements about the symmetry of prebisected lines. Visual stimuli consisted of symmetrically or asymmetrically transected lines, tachystoscopically presented for 50 ms on a computer-monitor. Performance was examined in basal condition and during rTMS trains of 10 stimuli at 25 Hz, delivered through a focal coil over right or left posterior parietal cortex (P5 and P6 sites) and triggered synchronously with visual stimulus. Randomly intermixed sham rTMS trains were employed to control for non-specific effects. Right parietal rTMS induced a significant rightward bias in symmetry judgements as compared with basal and sham rTMS conditions. No differences emerged between other conditions. NeuroReport 11:1519-1521 (C) 2000 Lippincott Williams & Wilkins.