Risk factors for infection by Acinetobacter baumannii in intubated patients with nosocomial pneumonia

Risk factors for infection by Acinetobacter baumannii in intubated patients with nosocomial pneumonia
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DOI:
10.1378/chest.112.4.1050
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发表时间:
1997-10-01
期刊:
影响因子:
9.6
通讯作者:
Rello, J
Rello, J
中科院分区:
医学1区
文献类型:
--
作者:
Baraibar, J;Correa, H;Rello, J

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Study objective: To investigate the epidemiology of infection by Acinetobacter baumannii patients with ventilator-associated pneumonia (VAP).Design: Prospective clinical study,Setting: Three medical-surgical ICUs in teaching hospitals.Patients: We followed up 707 mechanically-ventilated patients and 148 episodes of VAP with etiologic diagnosis.Results: A baumannii was isolated in 12 (8.1%) episodes in 148 patients. Five of these episodes mere directly responsible for death, Using logistic regression analysis, the risk of VAP due to A baumannii was found to be high in patients with neurosurgery (odds ratio [OR]=10.03; 95% confidence interval [CI]=1.55 to 64.90), ARDS (OR=9.73; 95% CI=1.60 to 59.24), head trauma (OR=5.17; 95% CI=0.88 to 30.34), and large-volume pulmonary aspiration (OR=2.90; 95% CI=0.80 to 10.53).Conclusions: Intubated patients Rho develop pneumonia and have any of the above factors are at an increased risk of Acinetobacter infection.