Nationwide outbreak of human salmonellosis in Germany due to contaminated paprika and paprika-powdered potato chips
Nationwide outbreak of human salmonellosis in Germany due to contaminated paprika and paprika-powdered potato chips
复制标题
DOI：
10.1017/s0950268800058660
复制
发表时间：
1995-12-01
影响因子：
4.2
通讯作者：
Aleksic, S
中科院分区：
文献类型：
--
作者：
Lehmacher, A;Bockemuhl, J;Aleksic, S
1993 年 4 月至 9 月期间，德国爆发了全国范围内的沙门氏菌病疫情，原因是受污染的辣椒粉和辣椒粉薯片。在估计的 1000 例病例中，14 岁以下的儿童主要受到影响。零食中的微生物含量为每克 0.04-0.45 个。感染剂量估计为 4-45 个生物体，感染率为万分之一。此次疫情的独特之处在于所涉及的血清型多种多样。 S. saintpaul、S. rubislaw 和 S. javiana 是在同一时期从辣椒粉、香料混合物、零食和患者中分离出来的。他们的克隆身份通过分子分型方法得到证实。此外，从辣椒制品和患者中分离出了罕见沙门氏菌 O 群的单相和非运动菌株。这是有记录的最大规模的因香料受污染而爆发的疫情，证明即使适应干燥状态的沙门氏菌数量极少也能引起疾病。
Between April and September 1993, a nationwide outbreak of salmonellosis occurred in Germany which was traced to contaminated paprika and paprika-powdered potato chips. Of the estimated 1000 cases, children below 14 years were principally affected. Levels of 0.04-0.45 organisms per gram were found in the snacks. The infective dose was estimated at 4-45 organisms with an attack rate of 1 in 10000 exposed persons. The unique feature of the outbreak was the variety of serovars involved. S. saintpaul, S. rubislaw and S. javiana were isolated during the same time period from paprika powder, spice mixtures, snacks and patients. Their clonal identity was confirmed by molecular typing methods. Furthermore, monophasic and non-motile strains of rare salmonella O-groups were isolated from both paprika products and patients. This is the largest documented outbreak due to contaminated spices which proved that even extremely low numbers of salmonellae adapted to the dry state were able to cause illness.