Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings.

Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings.
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DOI:
10.1016/j.ijid.2020.12.087
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发表时间:
2021-03
期刊:
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
影响因子:
--
通讯作者:
Ramon-Pardo P
Ramon-Pardo P
中科院分区:
其他
文献类型:
--
作者:
Lucien MAB;Canarie MF;Kilgore PE;Jean-Denis G;Fénélon N;Pierre M;Cerpa M;Joseph GA;Maki G;Zervos MJ;Dely P;Boncy J;Sati H;Rio AD;Ramon-Pardo P

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COVID-19在地球仪传播后,抗生素的消耗量增加。这与对COVID-19患者细菌重复感染的担忧有关。在低收入和中等收入国家(LMIC),细菌病原体的鉴定具有挑战性,因为没有现成且具有成本效益的临床或生物标志物可以有效区分细菌和病毒感染。幸运的是,面对COVID-19传播的威胁,人们越来越意识到抗菌药物管理计划以及感染预防和控制措施的重要性,这些措施有助于减少微生物负荷,从而减少病原体的传播,减少抗菌药物耐药性的传播。这些措施应得到改进,特别是在发展中国家。需要进行研究以评估COVID-19大流行期间全球抗菌素耐药性的演变,因为病原体不分国界。这一问题在发展中国家更为重要,因为这些国家缺乏关于耐药性模式的数据,传染性病原体传播的条件最佳,治疗资源次优。
The dissemination of COVID-19 around the globe has been followed by an increased consumption of antibiotics. This is related to the concern for bacterial superinfection in COVID-19 patients. The identification of bacterial pathogens is challenging in low and middle income countries (LMIC), as there are no readily-available and cost-effective clinical or biological markers that can effectively discriminate between bacterial and viral infections. Fortunately, faced with the threat of COVID-19 spread, there has been a growing awareness of the importance of antimicrobial stewardship programs, as well as infection prevention and control measures that could help reduce the microbial load and hence circulation of pathogens, with a reduction in dissemination of antimicrobial resistance. These measures should be improved particularly in developing countries. Studies need to be conducted to evaluate the worldwide evolution of antimicrobial resistance during the COVID-19 pandemic, because pathogens do not respect borders. This issue takes on even greater importance in developing countries, where data on resistance patterns are scarce, conditions for infectious pathogen transmission are optimal, and treatment resources are suboptimal.
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