Comparison between self-report and hair analysis of illicit drug use in a community sample of middle-aged men
Comparison between self-report and hair analysis of illicit drug use in a community sample of middle-aged men
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DOI：
10.1016/j.addbeh.2008.04.009
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发表时间：
2008-09-01
影响因子：
4.4
通讯作者：
Price, Rumi Kato
中科院分区：
文献类型：
--
作者：
Ledgerwood, David M.;Goldberger, Bruce A.;Price, Rumi Kato
非法药物使用的生物测定和自我报告之间的区别可能会破坏流行病学研究结果。本研究的两个目标是检查在社区中年男子样本中自我报告的非法药物使用和头发分析之间的一致程度，并确定可能预测自我报告和头发测试之间差异的因素。自1972年以来，男性参与者接受了有关物质使用的采访，并使用放射免疫分析和气相色谱-质谱（CC-MS）技术分析了大麻，可卡因，阿片类药物，苯环己哌啶（PCP）和甲基苯丙胺的头发样本。自我报告和毛发测试一般符合良好，但不是极好的协议。最近可卡因使用的明显少报与参与者最近一次戒烟尝试的住院治疗、年龄较小、被确定为非裔美国人或其他人以及未被诊断为反社会人格障碍有关。相对于毛发测试，对大麻使用的高估与自1972年以来的频繁使用以及提供的毛发样本不足有关。需要更多的研究来确定差异影响头发药物检测和自我报告有效性的因素。(C)2008爱思唯尔有限公司保留所有权利。
Discrepancies between biological assays and self-report of illicit drug use could undermine epidemiological research findings. Two objectives of the present study are to examine the degree of agreement between self-reported illicit drug use and hair analysis in a community sample of middle-aged men, and to identify factors that may predict discrepancies between self-report and hair testing. Male participants followed since 1972 were interviewed about substance use, and hair samples were analyzed for marijuana, cocaine, opiates, phencyclidine (PCP) and methamphetamine using radioimmunoassay and gas chromatography-mass spectrometry (CC-MS) techniques. Self-report and hair testing generally met good, but not excellent, agreement. Apparent underreporting of recent cocaine use was associated with inpatient hospitalization for the participant's most recent quit attempt, younger age, identifying as African American or other, and not having a diagnosis of antisocial personality disorder. The overestimate of marijuana use relative to hair test was associated with frequent use since 1972 and providing an inadequate hair sample. Additional research is needed to identify factors that differentially affect the validity of both hair drug testing and self-report. (C) 2008 Elsevier Ltd. All rights reserved.